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Angiogenesis in Health and Disease: Basic Mechanisms and Clinical Applications
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ISBN
:
9780824781026
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Publisher
:
Marcel Dekker
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Subject
:
Medical Study & Revision Guides & Reference Material
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Binding
:
Hardcover
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Pages
:
552
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Year
:
1999
₹
13087.0
₹
13087.0
13087.0
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Description
Outlines strategies for stimulating capillary formation in hypoxia and ischemia and inhibiting it in cancer, diabetes, and chronic inflammation. This state-of-the-science reference highlights recent progress in the ways to promote formation of new blood vessels in ischemic/hypoxic tissue and the means to stifle capillary growth and development in solid tumors, diabetic retinopathy, and chronic immuno/inflammatory disorders such as rheumatoid arthritis and psoriasis. Emphasizes practical clinical applications derived from the latest angiogenesis research. Written by over 80 leading international experts, Angiogenesis in Health and Disease -examines new angiogenic regulators such as angiopoietins and TIE-receptors -describes angiogenic genes such as thymosine B-4, EDG-1, and ARNT proteins -analyzes the role of vascular endothelial growth factor (VEGF) in capillary sprouting -investigates behaviors of endogenous agents of angiogenesis, including cytokines, hormones, chemokines, and peptide and hematopoietic growth factors -explores mechanisms for ameliorating or preventing vascular occlusive disease by induction of collateral artery growth -explains differences in conditions that prompt angiogenesis and arteriogenesis -reviews transgenic and knock-out mice, receptor protein mutations, and other emerging technologies -evaluates angiogenic inhibitors such as angiostatin and endostatin -and more Containing over 3000 references, tables, drawings, and photographs, Angiogenesis in Health and Disease deserves a prominent place on the bookshelves of cardiologists, oncologists, physiologists, hematologists, molecular and cell biologists, biochemists, pharmacologists, rheumatologists, vascularsurgeons, and upper-level undergraduate, graduate, and medical school students in these disciplines.
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