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Structured Based Drug Design 23.0%OFF

Structured Based Drug Design

by Veerapandian, Pandi Veerapandian and Pandi Veerapandian

  • ISBN

    :  

    9780824798697

  • Publisher

    :  

    Taylor & Francis/BSP Books

  • Subject

    :  

    Chemistry, Medical Study & Revision Guides & Reference Material

  • Binding

    :  

    Hardcover

  • Pages

    :  

    664

  • Year

    :  

    1997

₹

995.0

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766.0

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  • Description

    Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more

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