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Advances In Immunology, Volume 83: T Cell Subsets: Cellular Selection, Commitment And Identity 1st  Edition

Advances In Immunology, Volume 83: T Cell Subsets: Cellular Selection, Commitment And Identity 1st Edition

by Laurie Glimcher and Harvey Cantor

  • ISBN

    :  

    9780120224838

  • Publisher

    :  

    Academic Press

  • Subject

    :  

    Medical Study & Revision Guides & Reference Material

  • Binding

    :  

    Hardcover

  • Year

    :  

    2004

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  • Description

    This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

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