Alpha 1 - Antitrypsin Deficiency: Biology-Pathogenesis-Clinical Manifestations-Therapy 2nd Edition

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Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of a1AT deficiency, describes the a1AT gene and its promoter, and details specific therapies to prevent the major clinical manifestations of the disorder.