Download App
>> | LShop | >> | Book | >> | Medicine | >> | Medical Study & Revi... | >> | Gene Therapy For Can... |
ISBN
:
9781588294722
Publisher
:
Humana Press
Subject
:
Medical Study & Revision Guides & Reference Material
Binding
:
Hardcover
Year
:
2007
₹
23883.0
₹
22927.0
Buy Now
Shipping charges are applicable for books below Rs. 101.0
View Details(Imported Edition) Estimated Shipping Time : 25-28 Business Days
View DetailsDescription
The possibility of treating cancer, a disease frequently defined bygenetic defects, by introducing genes that target these veryalterations has generated tremendous enthusiasm. This enthusiasm,however, has been tempered by an increasing number of obstacles tosuccessful therapy, including vector systems that do not reach systemicmetastases, therapeutic genes with redundant mechanisms allowing forcellular resistance, and toxicities in clinical trials that result inpremature closure. The three comprehensive sections of this volumepresent currently available cancer gene therapy techniques, withspecific attention to these trouble spots. Part I describes the variousaspects of gene delivery including vehicles, or vectors, and theirrespective characteristics and production methods. In Part II, thecontributors discuss strategies and targets for the treatment ofcancer, including methods for cell-death therapies, correction ofunderlying genetic defects at the molecular level, and activation ofthe immune system or tumor microenvironment. The contributors provide asuccinct framework for understanding the basic underlying oncogenicchanges, which encourages the development of vectors engineered toexploit these gene mutations through selective spread of the vector intumor cells with the specific changes. Finally, in Part III, experts inclinical gene therapy trials discuss the difficulties inherent inbringing gene therapy treatment for cancer to the clinic, and principalinvestigators present gene therapy approaches in the clinical testingstage and the results that have reached the stage of clinicaltesting.of these trials.
Related Items
-
of
Complementary Therapies in Rehabilitation: Evidence for Efficay in Therapy, Prevention, and Wellness
Carol M. Davis
Starts At
3982.0
5455.0
27% OFF
Interventions, Effects, and Outcomes in Occupational Therapy: Adults and Older Adults
Mary C. Law
Starts At
2918.0
3839.85
24% OFF
Occupational Therapy Essentials for Clinical Competence
Karen Sladyk
Starts At
4231.0
5796.0
27% OFF
Occupational Therapy Interventions: Function and Occupations
Catherine Meriano
Starts At
3297.0
4517.0
27% OFF
Advances in Photodynamic Therapy: Basic, Translational and Clinical
Michael R. Hamblin
Starts At
13272.0
16386.0
19% OFF
Child-Centered Play Therapy Research: The Evidence Base for Effective Practice
Jennifer N. Baggerly
Starts At
5721.0
6653.0
14% OFF
Principles Of Pharmacology The Pathophysiologic Basis Of Drug Therapy 2/Ed
Golan David E. Et. Al.
Starts At
697.0
850.0
18% OFF
DNA Repair in Cancer Therapy: Molecular Targets and Clinical Applications
KELLEY MARK R.
Starts At
10049.0
11686.0
14% OFF
Recent Advances In Herbal Drug Research And Therapy
RAY ARUNABHA
Starts At
766.0
995.0
23% OFF
Advanced Play Therapy: Essential Conditions, Knowledge, and Skills for Child Practice [With CDROM]
Dee Ray
Starts At
11915.0
13094.0
9% OFF