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Genetics of Infectious Disease Susceptibility illustrated edition Edition
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ISBN
:
9780792371557
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Publisher
:
Springer
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Subject
:
Medical Study & Revision Guides & Reference Material
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Binding
:
Hardcover
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Year
:
2001
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14416.0
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Description
Infectious diseases have been major evolutionary forces throughout history and they have thus shaped our body and its defence mechanics. Nowadays they still kill at least 13 million people every year, mostly in the developing world, and many more are infected. Yet, we probably all remember infections spreading in households, classrooms, or countries, wondering why some get sick while others remained healthy. The purpose of this text is to promote and exploit that curiosity. It provides an overview of host genetic factors that provide complete or partial resistance to infection, that influence the clinical outcome of infection, or that give the capacity to remain healthy during infection. Progress in the molecular analysis of genetic susceptibility to human and animal infectious diseases has been very rapid over the last view years. Several genes involved in resistance to HIV/AIDS, tuberculosis, malaria, viral hepatitis, herpesvirus infections, prion diseases, and several others have now been identified, and their functions have partly or completely been elucidated. This book covers the most recent advances in the field and explores how progress in knowing the genetic basis of infectious diseases could lead to new insights into understanding and combating them.
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