Guide to Organic Stereochemistry

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About the BookIt takes the reader step-by-step from the structures of simple molecules, such as methane, to the basic shapes of biologically important macromolecules, such as proteins and nucleic acids. The concept of chirality is dealt with by firstly explaining the stereochemistry of compounds with one stereogenic centre, then dealing with compounds having two or more stereogenic centres before focusing on compounds possessing axes of chirality. The importance of stereochemistry in a wide variety of transformations (for example addition reactions, eliminations, and cycloadditions), is discussed. The final Chapters of Guide to Organic Stereochemistry describe the application of stereocontrol in asymmetric synthesis, indicating the use of chiral auxiliaries and chiral catalysts in modern chemistry.For Sale in Indian subcontinent onlyFeaturesSets itself out from other texts as it covers basic principles and terminology, and goes on to cover more advanced topics. Accessible to both the newcomer and the more experienced organic chemist. Includes well chosen examples to explain difficult concept while the reader is led to discussions of present day techniques. Includes 460 clear diagrams - helping the student assimilate complex information. Questions (and answers) included to help clarify complex issues.ContentsShapes of Simple Molecules Chirality in Molecules Containing Asymmetrically Substituted Tetrahedral Centres Nomenclature and Stereochemistry of Amino Acids and some Simple Carbohydrates Chirality in Systems Lacking an Asymmetric Carbon Atom Stereoisomerism about Bonds of Restricted Rotation: cis-trans isomerism Methods for Estimation of Ratios of Stereoisomers in a Mixture and the Separation and Identification of the Individual Components Some Transformations at or near a Stereogenic Centre: Racemisation and Resolution Some Simple Reactions of Carbonyl Compounds Stereochemistry of Some Important Reactions Leading to the Formation of Alkenes Some Reactions of Simple Alkenes Stereochemistry in Some Important Cyclizations Involving Pericyclic Reactions Stereochemistry of Cyclization Reactions Proceeding through High Energy Intermediates Stereochemistry of Selected Polymers Stereochemistry and Organic Synthesis Asymmetric Synthesis Total Asymmetric Syntheses of Prostaglandin F2 and Compactin