Introduction To Bioinformatics

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An Introduction to Bioinformatics introduces students to the immense power of bioinformatics as a set of scientific tools. The book explains how to access the data archives of genomes and proteins, and the kinds of questions these data and tools can answer: how to make inferences from the data archives, to make connections among them, and to derive useful and interesting predictions.Blending factual content with many opportunities for active learning, Introduction to Bioinformatics offers a truly reader-friendly way to get to grips with this subject, making it the ideal resource for anyone new to the field. The ideal text for anyone encountering bioinformatics for the first time. Strikes a careful balance between biology and computer science: introduces those aspects of computer science which underpin the subject without demanding detailed prior knowledge. Online Resource Centre includes figures from the book available to download, to facilitate lecture preparation, and a variety of interactive resources. Key Features New to this edition New chapter on biological organisation in space and time, mirroring recent advances in genomics, transcriptomics, proteomics and metabolomics. New chapter on scientific publications and archives, providing a state of the art inventory of how to source scientific literature. Expanded coverage of structural bioinformatics, reflecting recent breakthroughs in the subject area. Enhanced Online Resource Centre, with new guided tours of key websites, and lab assignments to support the in-depth exploration of concepts and themes covered in the

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Arthur Lesk Professor of Biochemistry and Molecular Biology, The Pennsylvania State University Table of Contents 1: Introduction 2: Genome organization and evolution 3: Scientific publications and archives: media, content and access 4: Archives and information retrieval 5: Alignments and phylogenetic trees 6: Structural bioinformatics and drug discovery 7: Proteomics and systems biology