Introduction to Protein Structure Prediction: Methods and Algorithms (Wiley Series in Bioinformatics)

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A look at the methods and algorithms used to predict protein structureA thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology.With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered:Databases and resources that are commonly used for protein structure prediction

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DR. HUZEFA RANGWALA is an assistant professor in computer science and bioengineering at George Mason University. He has published in various conferences and journals on the topic of bioinformatics.DR. GEORGE KARYPIS is a professor in computer science and engineering at the University of Minnesota. He has authored more than one hundred journal and conference papers and also serves on the editorial board of the International Journal of Data Mining and Bioinformatics.