Mitral Valve: Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation

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This book covers the entire spectrum of the floppy mitral valve/mitralvalve prolapse/mitral valve regurgitation triad.Few cardiac disorders have generated as much controversy and discussion overthe last two centuries as the floppy mitral valve (FMV)/ mitral valveproplapse (MVP)/ mitral valvular regurgitation (MVR) triad, and the mitralvalve prolapse syndrome. During the past 50 years, recognition of its broadpathologic and clinical spectrum has led to the appreciation of the FMV asthe central issue in the FMV/MVP/MVR story. Accordingly, the clinicalphenomena and imaging characteristics inherent in the FMV/MVP/MVR triad willbe best understood when reconciled with the gross morphologic,histopathologic, and molecular characteristics of the FMV complex.This book is written to cover the entire spectrum of FMV and its sequlae.The inheritance patterns, genetic studies, and development of familypedigrees; the relations of pathology and histology to FMV and clinicalfunctional expression; and the broad range of clinical presentation, are allexamined in depth. Complications (i.e. infective endocarditis,thromboembolic phenomena, arrhythmias, progressive MVR, chordae tendinaerupture, and left atrial and left ventricular dysfunction) are discussed indetail. Insights into the mechanismsof circulatory abnormalities and theirimpact on clinical phenomenon are also explored. Therapeutic approaches,including medical management and the indications and role of cardiacsurgery, are highlighted. Finally, a clinically useful classification forFMV/MVP patients is proposed.This book will be of interest to all cardiologists, including clinicalinvestigators, morphologists, physiologists, pathologists, surgeons, cardiacimagers, internists, family physicians, pediatricians, and nurse clinicians,and importantly, to discerning patients and individuals in search ofinformation about the FMV/MVP/MVR triad.