Outlines of Bioinformatics A student’s Compendium

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Outlines of Bioinformatics: A Students’ Compendium, is a first comprehensive book on the role of information technology in biological sciences. With advances in high performance computing, data management and the Internet, many new generation tools have been produced for studying gene and protein sequences, macro-molecular structures and metabolic systems. Thus aiding in the discovery of new drugs to change the way diseases are diagnosed and treated in future. This book provides on overview of Bioinformatics using central dogma as a theme. It explores the relationship of Molecular Biology and Bioinformatics to Computer Sciences. Bioinformatics is used by many researchers to access databases for Comparison and Sequence analysis. These are enriched and updated time to time for better results. Inside the book presents information about Gene and protein sequence networks, Human genome projects. Designed both for researchers and students, this book will become an indispensale aid to anyone seeking to understand the links between information technology & molecular biology. About The Author Mani Sharma is a Post graduate in Plant Sciences. She has done P.G. Diploma in Bioinformatics Drug Designing & Patenting. She has also done PGDBA. She is ex-faculty of Bioinformatics in DOEACC, Lucknow. (Barnch Chandigarh) As a student of Science she excelled throughout her academic career. With an emerged urge and commitment to pursue a systematic and formulated knowledge of modern sciences, she chose the field of Bioinformatics. A true science enthusiast, she believed in the adage, “The mind is a parachute which works best when open.” Table Of Contents PART I Molecular Biology The central dogma of molecular biology Overview of Gene structure Splicing The genetic material Open reading frames The RNA Alternative splicing The genetic code PART II Bioinformatics Introduction to bioinformatics challenges of bioinformatics applications of bioinformatics potential job sites journals Careers in Bioinformatics Introduction to information network Databases Substitution Matrix (PAM, Blosum) Sequence alignment Multiple sequence alignment Structural databases Phylogenetic analysis Neural network Orthologs, paralogs and xenologs Human genome project BLAST Web addresses