Tumors of the Pediatric Central Nervous System

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This is the first book to achieve an integrated medical and surgical approach to tumors of the pediatric nervous system, giving you a broad array of treatment options. You will find full coverage of the newest diagnostic and management techniques, state-of-the-art technologies, molecular biology advances, and the latest trends in the operating theatre. And you will benefit from in-depth discussions of the most commonly seen tumors as well as the rarer and more esoteric ones. Special benefits of Tumors of the Pediatric Nervous System include: Full discussions of medical and surgical treatment protocols, with advantages, disadvantages, complications, and outcomes of each Coverage of dramatic advances in genetics, molecular biology and surgery (e.g. endoscopic, frameless, stereotaxy) as well as chemotherapy, radiotherapy, and immunotherapy Dozens of case studies by leaders in the field offering important clinical insights Numerous algorithms, charts, tables, and management guidelines for at-a-glance summaries of key points Nearly 130 full-color pathologic slides Cost/benefit analysis integrated throughout Take advantage of this comprehensive approach to diagnosis and treatment that is so critical in today's health care environment. Whether you are a surgeon, oncologist, pediatrician or ancillary specialist, you will find a wealth of broad-based information that enhances patient care and leads to improved outcomes. Stay informed and up-to-date. Table of Contents Contributors Foreword Preface Section I Current Diagnosis and Therapeutic Approaches 1 Pediatric Neuro-oncology: A Historical Perspective, James Tait Goodrich 2 Epidemiology of Brain Tumors, Marc Bestak 3 Diagnostic Principles, Sarita Duchatelier and Steven M Wolf 4 Neuroradiology, Gilbert Vézina and Timothy N Booth 5 Surgical Neuropathology, Douglas C Miller 6 Anesthetic Considerations, Irene Osborn and Margaret Ekstein 7 Critical Care Considerations, Edward E Conway, Jr 8 Radiotherapy, Eugenio Vines, Helaine F Bertsch, and Joel W Goldwein 9 Stereotactic Radiosurgery, Douglas Kondziolka, L Dade Lunsford, and John C Flickinger 10 Chemotherapy, H Stacy Nicholson and Roger J Packer 11 Gene Therapy, Andrew T Parsa, David W Pincus, Neil A Feldstein, and Jeffrey N Bruce   Section II Intracranial Tumors 12 Infratentorial Astrocytoma, Michael D Medlock                                        13 Brain Stem Tumors, Keith S Blum and James Tait Goodrich                                 14 Supratentorial Astrocytoma, Philip V Theodosopoulos and Mitchel S Berger                15 Infratentorial Ependymoma, David M Weitman and Philip H Cogen                        16 Supratentorial Ependymoma, Charles L Rosen and Robert F Keating                      17 Infratentorial Primitive Neuroectodermal Tumors, Ian F Pollack                       18 Supratentorial Primitive Neuroectodermal Tumors, Ian F Pollack                       19 Craniopharyngioma, Jeffrey H Wisoff                                                  20 Pituitary Tumors, Marc S Arginteanu and Kalmon D Post                                21 Optic Nerve Glioma, Harold J Hoffman and Robin P Humphreys     22 Pineal Region Tumors, Andrew T Parsa, David W Pincus, Neil A Feldstein, Casilda M Balmaceda, Michael R Fetell, and Jeffrey N Bruce                              23 Phakomatoses, David M Weitman and Philip H Cogen                                    24 Choroid Plexus Tumors, Richard G Ellenbogen and Daniel J Donovan                    25 Intracranial Meningioma, Leon E Moores and Philip H Cogen                           26 Oligodendroglioma, Robert F Keating and Lisa Mulligan                               27 Extraneural Metastasis, David F Jimenez and Richard Teff                            28 Infantile Brain Tumors, Concezio Di Rocco, Aldo Iannelli, and Fabio Papacci         29 Miscellaneous Brain Tumors, Steven J Schneider and Salvatore A Insinga                Section III Spinal Cord Tumors 30 Astrocytoma, Cheryl A Muszynski, Shlomi Constantini, and Fred J Epstein             31 Ependymoma, Steven J Schneider and Alan D Rosenthal                                 32 Neurofibromatosis, James Tait Goodrich                                              33 Peripheral Nerve Tumors, Gavin Wayne Britz, Jang-Chul Lee, Robert Goodkin, and Michel Kliot                                                       34 Uncommon Pediatric Spinal Cord Tumors, Caple A Spence, Russell Buchanan, and Robert F Keating                                                                   Section IV Outcomes and Complications 35 Postoperative Considerations, Michael E Seiff and James Tait Goodrich             36 Rehabilitation, Subhadra L Nori and David Magill                                  37 Cooperative Group Trials, Roger J Packer, Richard Sposto, Henry Friedman, and Giorgio Perilongo                                                                38 Chemosensitivity Testing, Paul L Kornblith and Dennis R Burholt                   39 Late Effects of Therapy in Long-Term Survivors, H Stacy Nicholson and Robert Butler 40 Ethical Issues in Pediatric Neuro-oncology, Ann-Marie Yost                         Index