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An Introduction to Drug Design 1st Edition
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ISBN
:
9788122409437
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Publisher
:
New Age International
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Subject
:
Medical Study & Revision Guides & Reference Material
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Binding
:
Paperback
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157.5
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Description
The book entitled, An Introduction to Drug Design aims to optimize the discovery of drugs at a low cost and on occasions to change their pharmacokinetic and pharmacodyanamic properties. The introductory chapter which forms the basis of drug discovery is followed by the present-day thinking regarding the best approaches to drug discovery are considered. Similarly, there have been major advances in the employment of computers in structure-activity analysis, and a discussion of the state of the art in this area is also included. The chapter on QSAR highlights the role of physico-chemical parameters in predicting the future course of drug discovery with rational drug design. The role of enzymes in drug action is well established, and a chapter on design of enzyme inhibitors is well documented. In addition, the increased understanding of the design and utilisation of prodrugs has led to a discussion of the relevant issues in this text. Thus the book will fill the need of a text for designing new drugs and the principles of new drug discovery. Table of Contents Section I Development of New Drugs Section II Prodrugs and Soft Drugs Section III Chemical Parameters in Drug Design Section IV Physicochemical parameters in Drug Design Section V Design of Enzyme Inhibitors Section VI Drug Metabolism Section VII Molecular Modelling Using Computers Section VIII Structure-Based Drug Design.
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