Principles of Immunology Student???s Compendium 1st Edition

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The field of Immunology has undergone a period of explosive growth since the past twenty years. Immunology is now in an epoch of creative fervour that can be linked to the heroic decades when different pioneer scientists like Louis Pasteur, Robert Koch and their colleagues built the foundation of Microbiology. Immunology is deepening our understanding of disease processes and providing new diagnostic and therapeutics approaches, such as monoclonal antibodies which serve as an important tool for highly specific detectors of pathogenic micro-organisms, tissue damage, cancer and probe to detect differences in various antigens. The impact of immunology can well be exemplified by small pox eradication and various beneficial effects of vaccine for the control of dreadful epidemics of humans and livestock. Vaccine has become prisoner of their own success. A genuine renaissance in vaccinology research has brought forward what could be termed as a surfeit of riches. The most powerful development of all DNA vaccines have made their explosive entry, possibly signalling a revolutionin the science of vaccine based on their ease of production, stability and simplicity of combination. Host parasite relationship has been extensively dealt with to understand our protective force in relation to the forces found in the armamentarium of our enemy. Specific relevant information have been given in all the chapters. In this book there are twenty chapters. It has been recently observed that horizon of the study of immunology teaching is increasing as most of the vocational courses approved by the University Grants Commission has included immunology in its course curriculum. Thus, each chapter has been written, keeping in view the course outline of immunology in Medical, Veterinary (VCI course), Biotechnology, Bioinformatics and other vocational courses in which immunology has been included. Though it is an arduous task to include many advances made in the field, yet it has been tried to include multitude of complex and diverse information to make this text innovative, stimulatory and useful. Each chapter has been provided with multiple chocie question with answers in order to prepare students for various competitive examination. At the same time each chapter has been provided with required illustrations and tables. The research challenge in the filed of immunology is unbounded and have to go a long way in this field to reach the target. Apart from the the basic research there is a great need to emphasize upon its practical applications to bring respite to mankind. About the Author Dr. Basant Kumar Sinha, Retd. Retd. University Professor & Head Department of Microbiology, Bihar Veterinary College, Patna, Bihar, India, Obtained his Postgraduate and Ph.D. degree in Microbiology from All India Institute of Medical Science (AIIMS), New Delhi and Haryana Agriculture University, Hissar respectively. He has forty years of teaching experience both at UG and PG level and guided several M.Sc. students in Microbiology. He is also the visiting professor in Immunology and Biotechnology in different universities of Bihar and Jharkhand state and used to teach Immunology, Animal Cell Culture and Animal CellBiotechnology. He has also a brilliant career in research and handled several research projects funded by Indian Council of Agricultural Research (ICAR) and National Agriculture Technology Project (NATP), New Delhi, Government of India. He has published more than hundred research papers in National and International Journal of repute. Several awards have been won by him such as the prestigious ???Hamdard National Foundation Award??? for best research in Immunology, ???Academic Promotion Award??? and award for distinguished services at Rajendra Agriculture University, Pusa. Table of Contents Historical Development of immunology Host parasite relationshipImmunity Antigens, Antigenicity & immunogen Adjuvants Immunloglobulin Theory of antibody fromation Complement system Immmune system Cytokines Cellular basis of immume respnse Mucosal immunity Hypersensitivity Histocompatility complex Transplantation immunlogy Diversity of immunoglobulin Tolerance and autoimmune disease Tumour immunlogy Immunodiagnostic tools Vaccine and antiserum